Pathogenesis of striated muscle specific laminopathies: defining the developmental role of LITF in myogenesis and muscle regeneration.

横纹肌特异性核纤层蛋白病的发病机制：定义 LITF 在肌生成和肌肉再生中的发育作用。

• 批准号: 205292
• 负责人: Wu Kitty Y
• 金额: $ 0.36万
• 依托单位: University of Ottawa Heart Institute
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-03-01 至 2010-06-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=205292&lang=en
• 关键词: Gene Expression; Mouse Development; Mouse Genetics; Muscular Dystrophy

Genetic disorders caused by mutations in the Lamin A/C gene (LMNA) are defined as laminopathies and affect the muscle, heart and other organs. Muscular dystrophy (MD) is one of the most common muscle-related laminopathies that arises from specific mutatio

由核纤层蛋白A/C基因（LMNA）突变引起的遗传性疾病被定义为核纤层蛋白病，并影响肌肉，心脏和其他器官。肌营养不良（MD）是一种最常见的肌肉相关的层粘连蛋白病，由特定的突变引起，