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A transport metabolon in the apical membrane of the proximal tubule alters sodium and water (re)absorption

A transport metabolon in the apical membrane of the proximal tubule alters sodium and water (re)absorption
近端小管顶膜中的转运代谢改变钠和水的(再)吸收
批准号:
200061
负责人:
Alexander Robert T
金额:
$23.26万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2010
资助国家:
加拿大
项目状态:
已结题
起止时间:
2010-03-01 至 2013-03-01

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中文摘要
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英文摘要
Blood pressure is controlled by regulating the amount of sodium and water in the blood space. This regulation occurs in the kidney where daily 180L of blood is filtered and then 178-179L is reabsorbed back into the blood via a process that generates urine
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Leveraging a large cohort of patients with a unique, frequent renal sodium phosphate cotransporter, SLC34A3, pathogenic variation to understand and treat osteoporosis and kidney stones
  • 批准号:
    494218
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2023
  • 负责人:
    Alexander Robert T
  • 依托单位:
KRESCENT 2.0 HRTP Application for a SPOR Supplement: Proposal - SPOR Supplement
  • 批准号:
    463798
  • 项目类别:
    Directed Grant
  • 资助金额:
    $10.93万
  • 财政年份:
    2022
  • 负责人:
    Alexander Robert T
  • 依托单位:
Kidney Research Scientist Core Education and Training Program 2.0
  • 批准号:
    458410
  • 项目类别:
    Operating Grants
  • 资助金额:
    $174.84万
  • 财政年份:
    2021
  • 负责人:
    Alexander Robert T
  • 依托单位:
Canada Research Chair - Tier 2
  • 批准号:
    453867
  • 项目类别:
  • 资助金额:
    $36.43万
  • 财政年份:
    2020
  • 负责人:
    Alexander Robert T
  • 依托单位:
海外基金