Complex RNA regulatory networks in the human pathogen Leishmania and their role in developmental gene expression and pathogenesis

人类病原体利什曼原虫中复杂的RNA调控网络及其在发育基因表达和发病机制中的作用

• 批准号: 200444
• 负责人: Papadopoulou Barbara
• 金额: $ 55.78万
• 依托单位: Centre hospitalier de l'Universit Laval (Qubec)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-03-01 至 2015-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=200444&lang=en
• 关键词: 3'Utr Elements; Developmental Gene Regulation; Leishmania; Microarrays; Mrna Decay; Pathogenesis; Proteomics; Rna Regulatory Networks; Rna Sequencing; Rna Structure

Leishmania is an important human pathogen that causes leishmaniasis, a vector-borne parasitic disease with a large spectrum of clinical manifestations, and infects more than 12 million people worldwide. In order to survive within its mammalian host, Leish

利什曼原虫是一种重要的人类病原体，导致利什曼病，这是一种具有广泛临床表现的媒介传播寄生虫病，在全世界感染了1200多万人。为了在哺乳动物宿主中生存，