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Neuronal derived Semaphorin 3A contributes to vascular degeneration and misdirected pathological vessel growth in proliferative ischemic retinopathies

Neuronal derived Semaphorin 3A contributes to vascular degeneration and misdirected pathological vessel growth in proliferative ischemic retinopathies
神经元来源的信号蛋白 3A 导致增殖性缺血性视网膜病中的血管变性和错误的病理性血管生长
批准号:
201351
负责人:
Sapieha Przemyslaw (Mike) S
金额:
$47.06万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2010
资助国家:
加拿大
项目状态:
已结题
起止时间:
2010-03-01 至 2015-03-01

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中文摘要
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英文摘要
Diabetic retinopathy (DR) and retinopathy of prematurity (ROP) (collectively termed proliferative retinopathies (PRs)) are the leading causes of blindness in the world. Like a cancerous tumor, they are characterized by excessive blood vessel growth inside
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Impact of early life systemic metabolic deregulation on reprogramming of CNS microglia in retinal vascular disease
Past history of infection as a trigger of immune reprograming and neuroinflammation in late life.
  • 批准号:
    477247
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2022
  • 负责人:
    Sapieha Przemyslaw (Mike) S
  • 依托单位:
Canada Research Chairs - Tier 1
  • 批准号:
    441800
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2020
  • 负责人:
    Sapieha Przemyslaw (Mike) S
  • 依托单位:
Neurovascular and neuroimmune interplay in retinal vasculopathies
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