Molecular effects on bone mechanics: structural and mechanical studies of type-II collagen

对骨力学的分子效应：II 型胶原蛋白的结构和力学研究

• 批准号: 207731
• 负责人: Forde Nancy R
• 金额: $ 7.25万
• 依托单位: Simon Fraser University (Burnaby, B.C.)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-06-01 至 2011-06-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=207731&lang=en
• 关键词: Atomic Force Microscopy (Afm); Bone Development; Bone Health; Collagen; Fibrils; Mechanics; Optical Tweezers; Transmission Electron Microscopy (Tem)

Determining and predicting bone health is a challenging problem at all levels from clinical assessment of fracture risk to a microscopic understanding of the origin and likelihood of fractures. Fractured bones result in lost productivity and high cost to

确定和预测骨骼健康在各个层面都是一个具有挑战性的问题，从骨折风险的临床评估到对骨折起源和可能性的微观了解。 骨折导致生产力损失和高成本，