Identification of the gene(s) predisposing to Chiari Malformation I using the Griffon Bruxellois dog model

使用 Griffon Bruxellois 狗模型鉴定诱发 Chiari 畸形 I 的基因

• 批准号: 210129
• 负责人: Kibar Zoha
• 金额: $ 20.41万
• 依托单位: Centre hospitalier universitaire Sainte-Justine (Montral, Qubec)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-09-01 至 2013-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=210129&lang=en
• 关键词: Candidate Genes; Chiari Malformation I; Complex Traits; Dog Model; Functional Studies; Genetic Studies; Linkage Disequilibrium Mapping; Malformation Of The Craniovertebral Junction; Mutation Screening; Next Generation Sequencing

Chiari malformation I (CMI) represents a common abnormality of the lower region of the brain located at the junction with the spinal cord, with an estimated incidence of 1 in 1280. The lower portions of the brain called the cerebellar tonsils protrude int

Chiari畸形I （CMI）是一种位于脊髓连接处的大脑下部区域的常见异常，估计发病率为1 / 1280。大脑的下部被称为小脑扁桃体