Development of novel animal models to study the impact of metabolism on aging: Investigating the role of the AMP-activated protein kinase (AMPK)

开发新型动物模型来研究新陈代谢对衰老的影响：研究 AMP 激活蛋白激酶 (AMPK) 的作用

• 批准号: 228752
• 负责人: Jones Russell G
• 金额: $ 3.61万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-09-01 至 2011-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=228752&lang=en
• 关键词: Aging; Amp-Activated Protein Kinase (Ampk); Animal Models Of Aging; Cellular Metabolism; Reactive Oxygen Species (Ros); Senescence; Tumour Suppression

The growth, development and lifespan of an organism is intricately linked with nutrient availability and metabolism. The lifespan of many organisms, from simple organisms such as yeast and nematodes (worms) to complex species such as mice and primates, ca

生物体的生长、发育和寿命与营养物质的可利用性和新陈代谢密切相关。许多生物的寿命，从简单的生物如酵母和线虫（蠕虫）到复杂的物种如小鼠和灵长类动物，