Understanding the mechanism of Wolbachia-mediated antiviral protection

了解沃尔巴克氏体介导的抗病毒保护机制

• 批准号: DP1092492
• 负责人: A/Prof Karyn Johnson
• 金额: $ 29.26万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP1092492
• 关键词: Understanding; mechanism; Wolbachia; mediated; antiviral

Insects are involved in the transmission of many viral diseases of both plants and animals. A considerable number of these diseases have adverse effects for public health or cause large economic losses in agriculture. We were the first to discover that a common bacteria protects insects from virus infection. Knowledge of the mechanisms used by the bacteria to interfere with virus accumulation will facilitate novel strategies for control of virus disease. The findings of this project will enable Australian researchers and industry to design innovative approaches to control diseases that are transmitted by insects.

昆虫与动植物的许多病毒性疾病的传播有关。这些疾病中有相当一部分对公共卫生产生不利影响，或给农业造成巨大经济损失。我们是第一个发现一种普通的细菌可以保护昆虫免受病毒感染的人。了解细菌干扰病毒积累的机制将有助于控制病毒病的新策略。该项目的研究结果将使澳大利亚的研究人员和工业界能够设计创新的方法来控制昆虫传播的疾病。