Heteroclitic Stimulation and CD5 Modulation as Strategies to Expand Human Immunodeficiency Virus-specific CD8+ T cell Recognition Breadth

异斜刺激和 CD5 调节作为扩大人类免疫缺陷病毒特异性 CD8 T 细胞识别广度的策略

• 批准号: 215179
• 负责人: Grant Michael D
• 金额: $ 21.61万
• 依托单位: Memorial University of Newfoundland
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-09-01 至 2013-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=215179&lang=en
• 关键词: Cd5; Cd8; Heteroclitic; Hiv; Hla; Immunology; Peptide; T Cell

One of the biggest obstacles to developing an effective vaccine against human immunodfeficiency virus (HIV) is the tremendous diversity of the virus. This allows the virus to rapidly evade both antibody and T cell-mediated immune responses. The most com

开发针对人类免疫缺陷病毒（HIV）的有效疫苗的最大障碍之一是该病毒的巨大多样性。 这使得病毒能够快速逃避抗体和 T 细胞介导的免疫反应。 最com