Structural mechanisms of osmosensing and transport for proton-osmolyte symporter ProP of Escherichia coli

大肠杆菌质子渗透剂同向转运体 ProP 的渗透传感和运输结构机制

• 批准号: 210767
• 负责人: Wood Janet M
• 金额: $ 39.86万
• 依托单位: University of Guelph
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-09-01 至 2015-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=210767&lang=en
• 关键词: Cellular Osmoregulation; Cysteine Reactivity; Cysteine Scanning; Epr And Fluorescence Spectroscopies; Escherichia Coli; Kinetic Mechanism; Osmosensory Transporter Prop; Pegylation Assay

Living cells are perturbed by "osmosis", the flow of water into or out of cells in response to changes in the osmotic pressure of their environment. Cells must sense and respond to this osmotic stress because hydration changes perturb many cellular proces

活细胞受到“渗透”的干扰，即水流入或流出细胞以响应其环境渗透压的变化。细胞必须感觉到这种渗透压并作出反应，因为水合作用的变化扰乱了许多细胞过程