Characterization of the Interaction between Mycobacterium tuberculosis Protein Tyrosine Phosphatase A and Host Vacuolar H+-ATPase

结核分枝杆菌蛋白酪氨酸磷酸酶 A 与宿主液泡 H-ATP 酶之间相互作用的表征

• 批准号: 184522
• 负责人: Wong Dennis
• 金额: $ 7.65万
• 依托单位: Vancouver Coastal Health Research Institute
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2008
• 资助国家: 加拿大
• 起止时间: 2008-10-01 至 2011-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=184522&lang=en
• 关键词: Crystallography; Itraq Proteomics; Phagosome Maturation; Protein Tyrosine Phosphatase; Protein-Protein Interaction; Signal Transduction; Tuberculosis; Vacuolar H+-Atpase; Vesicular Trafficking

Our laboratory is researching on tuberculosis (TB), the leading cause of mortality due to a single infectious agent. We have identified a specific pathogenic mechanism by which Mycobacterium tuberculosis, the causative agent of TB, secretes a protein, Pro

我们的实验室正在研究结核病(TB)，这是单一感染源导致的主要死亡原因。我们已经确定了一种特殊的致病机制，即引起结核病的结核分枝杆菌分泌一种蛋白质Pro