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Cx32 specifically binds Sideroflexin-1 in neural progenitor cells and inhibits their differentiation to functional neurons following injury.

Cx32 specifically binds Sideroflexin-1 in neural progenitor cells and inhibits their differentiation to functional neurons following injury.
Cx32 特异性结合神经祖细胞中的 Sideroflexin-1，并抑制其在损伤后分化为功能性神经元。
批准号：
184710
负责人：
Fowler Stephanie L
金额：
$7.65万
依托单位：
University of Ottawa
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2008
资助国家：
加拿大
项目状态：
已结题
起止时间：
2008-10-01 至 2011-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=184710&lang=en
关键词：
Gap-Junctional Communication Immunofluoresence Mass Spectrometry Neural Progenitor Cell Fate Protein Interaction Mapping Tamoxifen-Inducible Reporter Mice Targeted Mutagenesis

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英文摘要
Connexin proteins are the structural units of gap junction channels, and form conduits between adjacent cells through which ions and signaling molecules may pass. Independent of their ability to form gap junction channels, connexin proteins mediate other
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