Cx32 specifically binds Sideroflexin-1 in neural progenitor cells and inhibits their differentiation to functional neurons following injury.

Cx32 特异性结合神经祖细胞中的 Sideroflexin-1，并抑制其在损伤后分化为功能性神经元。

• 批准号: 184710
• 负责人: Fowler Stephanie L
• 金额: $ 7.65万
• 依托单位: University of Ottawa
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2008
• 资助国家: 加拿大
• 起止时间: 2008-10-01 至 2011-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=184710&lang=en
• 关键词: Gap-Junctional Communication; Immunofluoresence; Mass Spectrometry; Neural Progenitor Cell Fate; Protein Interaction Mapping; Tamoxifen-Inducible Reporter Mice; Targeted Mutagenesis

Connexin proteins are the structural units of gap junction channels, and form conduits between adjacent cells through which ions and signaling molecules may pass. Independent of their ability to form gap junction channels, connexin proteins mediate other

连接蛋白是间隙连接通道的结构单位，在相邻细胞之间形成离子和信号分子可以通过的管道。独立于它们形成间隙连接通道的能力，连接蛋白介导其他