Identification and characterization of genes involved in the genesis and progression of pediatric astrocytomas.

参与儿童星形细胞瘤发生和进展的基因的鉴定和表征。

• 批准号: 224085
• 负责人: Jabado Nada
• 金额: $ 51.58万
• 依托单位: Research Institute of the McGill University Health Centre
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-03-01 至 2016-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=224085&lang=en
• 关键词: Astrocytomas; Biomarkers; Dna Methylation; Exome Sequencing; Gene Expression Profiling; Integrated Genomics; Mapk Signalling; Mouse Models; Pediatric Brain Tumour; Senescence

While overall survival for children with cancer has improved substantially over the last 3 decades, significant challenges remain. Specifically, a considerable proportion of childhood cancers remains incurable, or can only be cured with treatments that le

虽然癌症儿童的总体生存率在过去30年中大幅提高，但仍然存在重大挑战。具体来说，相当大比例的儿童癌症仍然无法治愈，或者只能通过治疗来治愈，