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Role of AMP-activated protein kinase in regulating inflammation in obesity: implications for the treatment of insulin resistance

Role of AMP-activated protein kinase in regulating inflammation in obesity: implications for the treatment of insulin resistance
AMP 激活蛋白激酶在调节肥胖炎症中的作用:对治疗胰岛素抵抗的影响
批准号:
223820
负责人:
Steinberg Gregory R
金额:
$49.58万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-03-01 至 2016-03-01

项目摘要

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中文摘要
翻译
近50%的加拿大人超重或肥胖。肥胖与炎症和脂肪代谢缺陷密切相关,而脂肪代谢缺陷会导致胰岛素抵抗(前驱糖尿病)。在目前的建议中,我们将研究代谢感觉素的作用
英文摘要
Nearly 50% of Canadian are overweight or obese. Obesity is strongly associated with inflammation and defects in fat metabolism which contribute to insulin resistance (pre-diabetes). In the current proposal we will examine the role for a metabolic sensin
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会议论文
10th international conference on AMPK: From mechanisms to new therapies
  • 批准号:
    383672
  • 项目类别:
    Miscellaneous Programs
  • 资助金额:
    $1.46万
  • 财政年份:
    2018
  • 负责人:
    Steinberg Gregory R
  • 依托单位:
Decrypting the Gut Microbiome to Identify New Therapies for NAFLD in Children and Adults
  • 批准号:
    399162
  • 项目类别:
    Operating Grants
  • 资助金额:
    $1.82万
  • 财政年份:
    2018
  • 负责人:
    Steinberg Gregory R
  • 依托单位:
Canada Research Chair - Tier 1 - CIHR Funded
  • 批准号:
    384880
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2017
  • 负责人:
    Steinberg Gregory R
  • 依托单位:
Energy Sensing and Metabolism: From Mechanisms to New Therapies
  • 批准号:
    368954
  • 项目类别:
    Operating Grants
  • 资助金额:
    $142.48万
  • 财政年份:
    2017
  • 负责人:
    Steinberg Gregory R
  • 依托单位:
海外基金