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Understanding telomerase function: modulation of a stable G-quadruplex structure in human telomerase RNA by the helicase RHAU.

Understanding telomerase function: modulation of a stable G-quadruplex structure in human telomerase RNA by the helicase RHAU.
了解端粒酶功能:通过解旋酶 RHAU 调节人端粒酶 RNA 中稳定的 G-四链体结构。
批准号:
234140
负责人:
McKenna Sean A
金额:
$7.29万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-03-01 至 2013-03-01

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中文摘要
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英文摘要
Human chromosome ends are protected from damage by a stretch of repetitive DNA sequences known as telomeres. In healthy mortal cells, telomere DNA is gradually shortened during successive rounds of replication as a cell ages, and therefore serves as a mol
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RiboWest Conference 2019
  • 批准号:
    404376
  • 项目类别:
    Miscellaneous Programs
  • 资助金额:
    $0.73万
  • 财政年份:
    2019
  • 负责人:
    McKenna Sean A
  • 依托单位:
Investigating BC200, a long non-coding RNA critical for cancer cell survival.
  • 批准号:
    410025
  • 项目类别:
    Operating Grants
  • 资助金额:
    $45.14万
  • 财政年份:
    2019
  • 负责人:
    McKenna Sean A
  • 依托单位:
Investigating the regulatory role of RNA-G4 helicases on telomerase activation.
  • 批准号:
    369810
  • 项目类别:
    Operating Grants
  • 资助金额:
    $57.12万
  • 财政年份:
    2017
  • 负责人:
    McKenna Sean A
  • 依托单位:
海外基金