Phosphoregulation of Disordered Protein Interactions in Neurobiology

神经生物学中无序蛋白质相互作用的磷酸调节

• 批准号: 226188
• 负责人: Forman-Kay Julie D
• 金额: $ 51.77万
• 依托单位: Hospital for Sick Children (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-03-01 至 2016-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=226188&lang=en
• 关键词: 4e-Bp2; Disordered State Structure; Dynamic Complexes; Eif4e; Nmda Receptor; Nuclear Magnetic Resonance Spectroscopy (Nmr); Phosphorylation; Protein Interactions; Saxs; Src

The brain is very complex and how it functions is currently not understood. We are studying specific mechanisms for controlling normal learning and memory that go awry in seizures, stroke, schizophrenia, chronic pain, autism, and brain cancers. This contr

大脑非常复杂，目前还不清楚它是如何运作的。我们正在研究控制正常学习和记忆的特殊机制，这些机制在癫痫发作、中风、精神分裂症、慢性疼痛、自闭症和脑癌中出错。此控制