Dynein/dynactin mutations associated with amyotrophic lateral sclerosis and their effect on axonal transport and neuromuscular junction formation in the zebrafish embryo.
Dynein/dynactin mutations associated with amyotrophic lateral sclerosis and their effect on axonal transport and neuromuscular junction formation in the zebrafish embryo.
与肌萎缩侧索硬化症相关的动力蛋白/动力蛋白突变及其对斑马鱼胚胎中轴突运输和神经肌肉接头形成的影响。
批准号：
307706
负责人：
Bercier Valrie
金额：
$7.65万
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2013
资助国家：
加拿大
项目状态：
已结题
起止时间：
2013-10-01 至 2016-10-01
中文摘要
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英文摘要
Amyotrophic lateral sclerosis (ALS) is an adult-onset fatal neurodegenerative disease, causing motor neuron degeneration, neuromuscular junction disruption, and muscle atrophy, which is mainly sporadic in nature. Mutations in the gene DCTN1, coding for th
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