Role of the interplay between the CTL pressure and HIV-1 restriction by TRIM5alpha in slow-progressor AIDS patients.

在慢速进展艾滋病患者中，CTL 压力与 TRIM5α 限制 HIV-1 之间相互作用的作用。

• 批准号: 300868
• 负责人: Merindol Natacha K
• 金额: $ 9.02万
• 依托单位: Universit du Qubec Trois-Rivières
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-11-01 至 2016-08-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=300868&lang=en
• 关键词: Capsid; Elite Controlers; Escape Mutations; Hiv-1; Immune Pressure; Restriction Factors; T Cell Response; Trim5alpha

More than 34 millions of people are infected with HIV-1 worldwide and over 25 millions have already died of AIDS. In 2011, about 71300 Canadians were living with HIV/AIDS, including 25% that were unaware of their infection. AIDS patients show high variab

全世界有3 400多万人感染了HIV-1，2 500多万人已经死于艾滋病。 2011年，约有71300名加拿大人感染艾滋病毒/艾滋病，其中25%的人不知道自己感染了艾滋病毒。艾滋病患者表现出高变异性