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Effects of chronic D2/3 agonist ropinirole medication and a D4 antagonist on gambling behaviour in a 6-OHDA rodent model of Parkinson's disease

Effects of chronic D2/3 agonist ropinirole medication and a D4 antagonist on gambling behaviour in a 6-OHDA rodent model of Parkinson's disease
慢性 D2/3 激动剂罗匹尼罗药物和 D4 拮抗剂对帕金森病 6-OHDA 啮齿动物模型赌博行为的影响
批准号：
307770
负责人：
Tremblay Melanie
金额：
$7.65万
依托单位：
University of British Columbia
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2013
资助国家：
加拿大
项目状态：
已结题
起止时间：
2013-10-01 至 2016-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=307770&lang=en
关键词：
Animal Model Chemical Lesions Decision-Making Dopamine Gambling Parkinson'S Disease Pharmacology Striatum

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英文摘要
This project aims to investigate the involvement of specific dopamine receptors on models of gambling behaviour, both in normal rats and in a rodent model of Parkinson's disease (PD). The more traditional drug treatment for PD, L-DOPA, has been shown over
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