Enhancing Epitope Presentation in Latent HIV+ T cells Upon Reactivation

增强潜伏 HIV T 细胞重新激活后的表位呈现

• 批准号: 327889
• 负责人: Kuang Xiaomei T
• 金额: $ 7.65万
• 依托单位: Simon Fraser University (Burnaby, B.C.)
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2014
• 资助国家: 加拿大
• 起止时间: 2014-10-01 至 2017-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=327889&lang=en
• 关键词: Anti-Latency Agents; Epitope Presentation; Hiv-1 Gag; Hiv-1 Latency; Hiv-1 Reactivation

Combination antiretroviral therapy can effectively treat HIV; however, it must be maintained for life due to HIV's ability to establish reservoirs of latently infected cells that are not affected by antiviral drugs and remain invisible to the immune syste

联合抗逆转录病毒疗法可以有效治疗艾滋病毒，但是，由于艾滋病毒能够建立潜伏感染细胞的储库，这些细胞不受抗病毒药物的影响，并且对免疫系统不可见，因此必须终身维持这种疗法。