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Enhancing Epitope Presentation in Latent HIV+ T cells Upon Reactivation

Enhancing Epitope Presentation in Latent HIV+ T cells Upon Reactivation
增强潜伏 HIV T 细胞重新激活后的表位呈现
批准号:
327889
负责人:
Kuang Xiaomei T
金额:
$7.65万
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2014
资助国家:
加拿大
项目状态:
已结题
起止时间:
2014-10-01 至 2017-10-01

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中文摘要
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英文摘要
Combination antiretroviral therapy can effectively treat HIV; however, it must be maintained for life due to HIV's ability to establish reservoirs of latently infected cells that are not affected by antiviral drugs and remain invisible to the immune syste
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HIV-1 Nef is required for efficient latency reversal in a T cell line
Enhancing Epitope Presentation in Latent HIV+ T cells Upon Reactivation
Inefficient HIV Gag Epitope Presentation During Reactivation from Latency
Impaired Early HIV-1 Nef Function in Spontaneous Viremic Controllers
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