Point of Care Device for Rapid Quantification of Cell-Free DNA with Application in Severe Sepsis

用于快速定量游离 DNA 的护理设备在严重脓毒症中的应用

• 批准号: 336652
• 负责人: Fox-Robichaud Alison E
• 金额: $ 17.51万
• 依托单位: McMaster University
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-10-01 至 2018-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=336652&lang=en
• 关键词: Biomedical Engineering 1102; Biomedical Technology 1901; Cell Free Dna; Medical And Health Sciences 1211; Microfluidics; Nucleic Acid 5402; Point Of Care Device; Prognosis; Sepsis; Whole Blood

Sepsis, the whole body response to infection, is associated with a high risk of intensive care unit admission, organ damage and death. Our clinical work has demonstrated that free DNA (cfDNA) released from cells into the bloodstream is a very strong predi

败血症是全身对感染的反应，与重症监护病房住院、器官损伤和死亡的高风险相关。我们的临床工作已经证明，游离DNA （cfDNA）从细胞释放到血液中是一个非常强大的predi