Life course-adjusted associations between intrauterine environment and DNA methylation in young adult women of a Jerusalem Perinatal Study sub-cohort.

耶路撒冷围产期研究子队列中年轻成年女性的宫内环境与 DNA 甲基化之间的生命历程调整关联。

• 批准号: 335719
• 负责人: Huang Jonathan Y
• 金额: $ 0.11万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-10-01 至 2016-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=335719&lang=en
• 关键词: Candidate Genes; Developmental Origins For Health And Disease; Dna Methylation; Epidemiology; Epigenetics; G-Formula; Life Course; Marginal Structural Models; Statistical Methods; Women'S Health

Excessive weight gain by a mother during pregnancy may adversely affect the development of her baby in the womb. In turn, this may be detrimental to the child's heart health and metabolism later in life. However, little is currently known about how these

母亲在怀孕期间体重增加过多可能会对胎儿在子宫内的发育产生不利影响。反过来，这可能对孩子以后的心脏健康和新陈代谢有害。然而，目前对这些如何