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PET and SPECT Probes for the Diagnosis of Alzheimer's Disease Targeting Cholinesterase Activity

PET and SPECT Probes for the Diagnosis of Alzheimer's Disease Targeting Cholinesterase Activity
针对胆碱酯酶活性用于诊断阿尔茨海默病的 PET 和 SPECT 探针
批准号:
354430
负责人:
Darvesh Sultan
金额:
$106.17万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-10-01 至 2021-10-01

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中文摘要
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英文摘要
Cholinesterases are enzymes involved in the breakdown of acetylcholine, a neurotransmitter, important in brain cell communication, that is reduced in Alzheimer's disease (AD). AD is marked by loss of memory and deposition of abnormal proteins toxic to bra
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Alternative FDG-PET relative standardized uptake value metrics for the assessment of early metabolic biomarkers of Alzheimer's disease
  • 批准号:
    293585
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.25万
  • 财政年份:
    2013
  • 负责人:
    Darvesh Sultan
  • 依托单位:
Synthesis and Evaluation of Butyrylcholinesterase Ligands as Brain Molecular Imaging Biomarkers for Alzheimer Disease
  • 批准号:
    237554
  • 项目类别:
    Operating Grants
  • 资助金额:
    $28.26万
  • 财政年份:
    2011
  • 负责人:
    Darvesh Sultan
  • 依托单位:
Synthesis and Evaluation of Butyrylcholinesterase Ligands for Brain Imaging in Dementia
  • 批准号:
    234358
  • 项目类别:
    Operating Grants
  • 资助金额:
    $3.91万
  • 财政年份:
    2011
  • 负责人:
    Darvesh Sultan
  • 依托单位:
Butyrycholinesterase activity and beta-amyloid plaques in mouse model of Alzheimer's disease.
  • 批准号:
    228733
  • 项目类别:
    Operating Grants
  • 资助金额:
    $3.64万
  • 财政年份:
    2010
  • 负责人:
    Darvesh Sultan
  • 依托单位:
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