The role of Alternative polyadenylation in the regulation of HMGB1 expression

选择性多腺苷酸化在 HMGB1 表达调节中的作用

• 批准号: 367326
• 负责人: Sadek Jason
• 金额: $ 1.27万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-12-01 至 2017-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=367326&lang=en
• 关键词: Alternative Polyadenylation; Hmgb1 Alarmin; Post-Transcriptional Regulation; Rna Binding Protein; Secretory Phenotype Of Inflammation; Translation Regulation

A fundamental theme in living organisms is that genetic information encoded in DNA is transcribed to form messenger RNA (mRNA), which is then translated to produce proteins. After transcription, mRNA undergoes processing to keep it stable within the cell

生物体的一个基本主题是DNA中编码的遗传信息被转录形成信使RNA（mRNA），然后被翻译产生蛋白质。转录后，mRNA经历加工以保持其在细胞内的稳定