ICOS signaling in T cell tolerance and gut homeostasis

T 细胞耐受和肠道稳态​​中的 ICOS 信号传导

• 批准号: 380233
• 负责人: Suh Woong-Kyung
• 金额: $ 65.2万
• 依托单位: Institut de recherches cliniques de Montral
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-03-01 至 2023-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=380233&lang=en
• 关键词: Gut Microbiota; Inducible Costimulator (Icos); Innate Lymphoid Cells (Ilc); Non-Obese Diabetic (Nod) Mouse; Regulatory T Cell (Treg); Signal Transduction; T Cell Costimulation

Our immune system works under two major rules: i) recognize and destroy pathogens ii) do not harm body's own cells. Failure of the first rule causes immunodeficiency whereas breach of the second rule leads to autoimmune diseases. White blood cells terme

我们的免疫系统在两个主要规则下工作：1)识别和摧毁病原体2)不伤害人体自身细胞。第一个规则的失败导致免疫缺陷，而第二个规则的破坏导致自身免疫性疾病。白血球是我的术语