Molecular mechanisms controlling the phase behavior and biosynthetic activity of the nucleolus

控制核仁相行为和生物合成活性的分子机制

• 批准号: 380870
• 负责人: Weber Stephanie C
• 金额: $ 47.37万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-03-01 至 2023-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=380870&lang=en
• 关键词: Dormancy; Intracellular Phase Transitions; Membraneless Organelles; Multicellular Growth; Nucleolus; Ribosome Biogenesis; Rrna Processing; Transcription

Living cells are divided into specialized compartments called organelles. Typically, membranes form a selective barrier between organelles and the cytoplasm, such that each compartment can maintain a distinct biochemical composition that is tailored to it

活细胞被分成称为细胞器的专门隔室。典型地，膜在细胞器和细胞质之间形成选择性屏障，使得每个隔室可以维持为其定制的独特的生化组成