The role of natriuretic peptide receptors in regulating electrical conduction and structural remodeling of the sinoatrial node in a mouse model of hypertensive heart disease.

钠尿肽受体在高血压心脏病小鼠模型中调节窦房结电传导和结构重塑中的作用。

• 批准号: 404106
• 负责人: Mackasey Martin
• 金额: $ 7.65万
• 依托单位: University of Calgary
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-10-01 至 2021-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=404106&lang=en
• 关键词: Atrial Fibrillation; Cardiac Fibrosis; Cardiovascular Disease; Electrophysiology; Gene Expression; Heart Failure; Histology; Natriuretic Peptides; Optical Mapping; Sinoatrial Node Disease

Cardiovascular diseases are the leading cause of death globally. They are often associated with the generation of arrhythmias (abnormal patterns in the heart beat), including sinoatrial node arrhythmias and atrial fibrillation, that increase morbidity and

心血管疾病是全球死亡的主要原因。它们通常与心律失常（心脏跳动中的异常模式）的产生相关，包括窦房结心律失常和心房颤动，这增加了发病率，