Mechanistic studies of macrophages and the tumour microenvironment as immunologic barriers to therapy in pancreatic ductal adenocarcinoma
Mechanistic studies of macrophages and the tumour microenvironment as immunologic barriers to therapy in pancreatic ductal adenocarcinoma
批准号:
387747
负责人:
McGaha Tracy
金额:
$77.19万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-09-01 至 2023-09-01
中文摘要
胰腺癌是最致命的癌症,5年生存率不到5%。造成这种情况的主要原因之一是对化疗和免疫治疗的抵抗力。我们预测阻力的机械驱动因素是应力信号的汇合。
英文摘要
Pancreatic cancer is the most lethal form of cancer with 5-year survival rates less than 5%. One of the principle reasons for this is resistance to chemo- and immune-therapy. We predict a mechanistic driver of resistance is a confluence of stress signals
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会议论文
Investigation of microbiome-aryl hydrocarbon receptor crosstalk and immune suppression in pancreatic cancer
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批准号:418937
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项目类别:Operating Grants
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资助金额:$74.12万
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财政年份:2020
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负责人:McGaha Tracy
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依托单位:
海外基金