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Mechanisms Underlying Corticosteroid Insensitivity Induction by Interleukin-17A in Bronchial Epithelial Cells

Mechanisms Underlying Corticosteroid Insensitivity Induction by Interleukin-17A in Bronchial Epithelial Cells
支气管上皮细胞中白细胞介素 17A 诱导皮质类固醇不敏感的机制
批准号：
400561
负责人：
Akik Wided
金额：
$0.07万
依托单位：
Research Institute of the McGill University Health Centre
依托单位国家：
加拿大
项目类别：
财政年份：
2019
资助国家：
加拿大
项目状态：
已结题
起止时间：
2019-01-01 至 2020-01-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=400561&lang=en
关键词：
Airway Epithelial Cells Corticosteroid Insensitivity Interleukin-17a Interleukin-8 Severe Neutrophilic Asthma

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Asthma is a heterogeneous chronic obstructive lung disorder that is characterized by an invasion of inflammatory cells in the lung. Inhaled corticosteroids are typically used for the treatment of asthma. However, up to 10% of patients can be insensitive t
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