Investigating the mechanisms of iron delivery to mitochondria.

研究铁递送至线粒体的机制。

• 批准号: 400893
• 负责人: McBride Heidi M
• 金额: $ 71.89万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-03-01 至 2024-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=400893&lang=en
• 关键词: Endosome; Ferroptosis; Friedreich'S Ataxia; Iron Disease; Iron Transport; Mitochondria; Rab5

Iron is an essential metal for life. However, it is also very reactive and just as it can rust in your car, it can also be oxidized in the cell, causing chain reactions that damage cells, tissues, and cause disease. In fact there are many diseases where i

铁是生命所必需的金属。然而，它也非常活跃，就像它可以在你的车里生锈一样，它也可以在细胞中氧化，引起连锁反应，损害细胞，组织，并引起疾病。事实上，有许多疾病，