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Microglia-neuron inflammatory interactions in Parkinson's disease: Targeting LRRK2 and WAVE2.

Microglia-neuron inflammatory interactions in Parkinson's disease: Targeting LRRK2 and WAVE2.
帕金森病中小胶质细胞-神经元炎症相互作用:针对 LRRK2 和 WAVE2。
批准号:
401809
负责人:
Hayley Shawn P
金额:
$42.08万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-03-01 至 2024-03-01

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中文摘要
翻译
已经确定的是,炎症免疫系统在正常情况下与大脑沟通,并且在疾病期间变得特别重要。大脑中的小胶质细胞充当专门的免疫细胞。 Whi
英文摘要
It has become well established that the inflammatory immune system communicates with the brain under normal circumstances and that it becomes particularly important during times of disease. Microglia within the brain act as specialized immune cells. Whi
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A multi-hit model of Parkinson's disease: LRRKing inflammatory mechanisms.
  • 批准号:
    321125
  • 项目类别:
    Operating Grants
  • 资助金额:
    $39.99万
  • 财政年份:
    2015
  • 负责人:
    Hayley Shawn P
  • 依托单位:
An ecologically minded multiple hit hypothesis of Parkinsonism: Inflammatory processes.
  • 批准号:
    180651
  • 项目类别:
    Operating Grants
  • 资助金额:
    $48.58万
  • 财政年份:
    2009
  • 负责人:
    Hayley Shawn P
  • 依托单位:
An ecologically minded multiple hit hypothesis of Parkinsonism: Inflammatory processes.
  • 批准号:
    178996
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2008
  • 负责人:
    Hayley Shawn P
  • 依托单位:
A focus on environmental triggers and neuronal mechanisms of depressive and other psychiatric co-morbidity in Parkinson's disease: From experimental studies to clinical translation.
  • 批准号:
    175907
  • 项目类别:
    Operating Grants
  • 资助金额:
    $0.0万
  • 财政年份:
    2008
  • 负责人:
    Hayley Shawn P
  • 依托单位:
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