Tumour microenvironment mediated cell surface shedding creates unique targets and markers

肿瘤微环境介导的细胞表面脱落创造了独特的靶标和标记

• 批准号: 415202
• 负责人: Lange Philipp
• 金额: $ 1.82万
• 依托单位: BC Children's Hospital Research Institute
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-09-01 至 2020-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=415202&lang=en
• 关键词: Cancer; Innovative Cancer Targets & Markers; Leukemia; Microenvironment; Neo-Antigen; Post-Translational Modification; Proteolysis; Proteomics; Tumor Antigens

Traditional chemo- and radiation-therapy, though often effective, has serious side and long-term effects, particularly for children, who face significant life-long health problems and increased risk for secondary cancers. We need to develop new "targeted

传统的化疗和放疗虽然通常有效，但有严重的副作用和长期影响，特别是对儿童，他们面临着严重的终身健康问题和继发性癌症的风险增加。我们需要开发新的“有针对性的