Understanding the role of TNFR1 signaling in malignant transformation of oral keratinocytes

了解 TNFR1 信号在口腔角质形成细胞恶性转化中的作用

• 批准号: 415151
• 负责人: Magalhaes Marco A
• 金额: $ 7.29万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-09-01 至 2020-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=415151&lang=en
• 关键词: Inflammation; Invadopodia; Keratinocytes; Oral; Tnf; Transformation

The oral cavity is a unique environment that combines complex bacterial biofilms, saliva and fine-balanced mechanisms of innate and cellular immunity. Numerous conditions that manifest in the oral cavity, including potentially malignant oral dysplasia and

口腔是一个独特的环境，结合了复杂的细菌生物膜，唾液和先天和细胞免疫的精细平衡机制。口腔中出现的许多疾病，包括潜在的恶性口腔发育不良和