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Analyses of the molecular roles of Tubby, the founding member of the developmentally important TUB Domain protein family

Analyses of the molecular roles of Tubby, the founding member of the developmentally important TUB Domain protein family
对发育重要的 TUB 结构域蛋白家族的创始成员 Tubby 的分子作用进行分析
批准号:
410209
负责人:
Cordes Sabine P
金额:
$73.29万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-09-01 至 2024-09-01

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中文摘要
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英文摘要
In mice and humans, mutations in the Tubby (Tub) gene cause maturity-onset obesity, insulin resistance, and retinitis pigmentosa. Tub and the related Tub-like proteins Tulp1, 2, 3 and 4 all contain a novel nucleic acid binding domain - the TUB domain. Mut
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Canada Research Chair - Tier 1
  • 批准号:
    404326
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2018
  • 负责人:
    Cordes Sabine P
  • 依托单位:
Analyzing the roles of the Gumby/Fam105b linear deubiquitinase in development and disease
Analyses of Polycomb group (PcG)/trithorax group(trxG) dependent mechanisms governing vertebrate neural development
Analysis of the role of the Gumby gene in angiogenesis
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