Colonic mucin biosynthesis, secretion and function in infectious diseases

结肠粘蛋白生物合成、分泌及其在传染病中的功能

• 批准号: 418754
• 负责人: Chadee Khrisendath
• 金额: $ 72.03万
• 依托单位: University of Calgary
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-03-01 至 2025-03-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=418754&lang=en
• 关键词: Entamoeba Histolytica; Fcgbp; Muc2 Mucin; Mucus; Mucus Associated Protein; Mucus Degradation; Mucus Protective Functions; Proteolytic Enzyme

Entamoeba histolytica is a parasite that cause the disease amebiasis, which results in 100,000 deaths/year. The parasite colonizes and live in mucus and feeds on bacteria. To initiate disease, the parasite has to overcome the protective mucus barrier to

溶组织内阿米巴是引起阿米巴病的寄生虫，每年导致100，000人死亡。这种寄生虫在粘液中定居和生活，以细菌为食。 为了引发疾病，寄生虫必须克服保护性粘液屏障，