Novel Pharmacological Approaches for the Treatment of HIV-Associated Neurological Complications

治疗 HIV 相关神经并发症的新药理学方法

• 批准号: 434192
• 负责人: Bendayan Reina
• 金额: $ 49.04万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-10-01 至 2025-10-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=434192&lang=en
• 关键词: Animal Behavioural Studies; Brain Inflammatory Markers; Ecohiv Mouse Model; Hiv Neurocognitive Disorders (Hand); Hiv-1 Infection; Hiv-Associated Brain Inflammation; Peroxisome Proliferator-Activated Receptors (Ppars); Pharmacokinetic Studies; Pharmacologi

Over 37 million people are infected by HIV-1 worldwide and up to 50% of these patients can develop HIV-associated neurocognitive disorders that highly impair their quality of life. It is well established that antiretroviral drugs are not as effective in t

全世界有超过3700万人感染艾滋病毒-1，其中高达50%的患者可发展为与艾滋病毒相关的神经认知障碍，严重影响其生活质量。众所周知，抗逆转录病毒药物对艾滋病没有那么有效