Investigating Immune Responses to HIV/TB Co-infection in Humanized Mice

研究人源化小鼠对 HIV/TB 合并感染的免疫反应

• 批准号: 449481
• 负责人: Yang Jack (Xiaozhi)
• 金额: $ 1.27万
• 依托单位: McMaster University
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-12-01 至 2021-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=449481&lang=en
• 关键词: Cytokines; Disease Dissemination; Granuloma; Hiv Tb Co-Infection; Human Immunodeficiency Virus; Humanized Mice; Immune Evasion And Homeostasis; Macrophages; T Cells; Tuberculosis

The bacteria Mycobacterium tuberculosis that causes latent or active tuberculosis (TB) disease has infected 1/4 to 1/3 of the human population. Unfortunately, the risk of latent TB developing into the contagious and deadly active TB can be increased by ov

引起潜伏性或活动性结核病（TB）的细菌结核分枝杆菌（Mycobacterium tuberculosis）已经感染了1/4至1/3的人口。不幸的是，潜伏性结核病发展成具有传染性和致命性的活动性结核病的风险可能会增加超过100万美元。