Elucidating the Role of TARDBP Mutation in Amyotrophic Lateral Sclerosis

阐明 TARDBP 突变在肌萎缩侧索硬化症中的作用

• 批准号: 454708
• 负责人: Moutaoufik Mohamed Taha
• 金额: $ 9.83万
• 依托单位: University of Regina (Saskatchewan)
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-10-01 至 2024-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=454708&lang=en
• 关键词: Amyotrophic Lateral Sclerosis; Biochemical Fractionation; Interaction Network; Motor Neurone Disease; Neurological Disorder; Protein Complexes; Proteomics; Tardbp

Amyotrophic lateral sclerosis (ALS) is characterized by progressive muscle atrophy due to the degeneration of neurons. Patients gradually lose their ability to walk, talk, eat and breathe, which subsequently leads to death. ALS is projected to increase gr

肌萎缩侧索硬化症（ALS）的特征在于由于神经元变性而导致的进行性肌肉萎缩。患者逐渐失去行走、说话、进食和呼吸的能力，最终导致死亡。预计ALS将增加GR