Determine how the interaction between SARS-CoV-2 spike protein and angiotensin-converting enzyme 2 (ACE2) affect viral spread and the severity of COVID-19 outcomes.
Determine how the interaction between SARS-CoV-2 spike protein and angiotensin-converting enzyme 2 (ACE2) affect viral spread and the severity of COVID-19 outcomes.
确定 SARS-CoV-2 刺突蛋白和血管紧张素转换酶 2 (ACE2) 之间的相互作用如何影响病毒传播和 COVID-19 结果的严重程度。
批准号：
449017
负责人：
Su Ruey-Chyi
金额：
$31.4万
依托单位：
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2021
资助国家：
加拿大
项目状态：
已结题
起止时间：
2021-04-01 至 2022-04-01
中文摘要
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英文摘要
The proposed research focuses on investigating why the SARS-CoV-2 variant, B.1.1.7 that have higher binding affinity to Angiotensin Converting Enzyme 2 (ACE2) on host cells are associated with increased viral spread and mortality rates. ACE2, the main re
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Elucidating the role of cell homing pathways in controlling endothelial cell-mediated enhancement of resting CD4+ T cell infection by HIV
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批准号：366806
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项目类别：Operating Grants
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资助金额：$15.05万
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财政年份：2017
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负责人：Su Ruey-Chyi
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依托单位：
海外基金
