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Targeting cancer-associated fibroblasts and tumour hypoxia with angiotensin II receptor blockers

Targeting cancer-associated fibroblasts and tumour hypoxia with angiotensin II receptor blockers
使用血管紧张素 II 受体阻滞剂靶向癌症相关成纤维细胞和肿瘤缺氧
批准号:
445961
负责人:
Bennewith Kevin L
金额:
$71.33万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2021
资助国家:
加拿大
项目状态:
未结题
起止时间:
2021-04-01 至 2026-04-01

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中文摘要
翻译
与正常组织中的细胞相比,实体肿瘤中的细胞可以在较低的氧气水平下生存。这些低氧(低氧)的肿瘤细胞更难用放射或化疗杀死,低氧的肿瘤细胞可以扩散(转移
英文摘要
Solid tumours can contain cells that exist at lower oxygen levels than cells found in normal tissues. These poorly oxygenated (hypoxic) tumour cells are more difficult to kill using radiation or chemotherapy, and hypoxic tumour cells can spread (metastasi
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会议论文
Hypoxia in tumour-draining lymph nodes as an indication of immune activation and immunotherapy response
  • 批准号:
    382068
  • 项目类别:
    Operating Grants
  • 资助金额:
    $69.66万
  • 财政年份:
    2018
  • 负责人:
    Bennewith Kevin L
  • 依托单位:
Promotion of breast cancer metastasis by tumour hypoxia and myeloid cells.
  • 批准号:
    266810
  • 项目类别:
    Operating Grants
  • 资助金额:
    $50.95万
  • 财政年份:
    2012
  • 负责人:
    Bennewith Kevin L
  • 依托单位:
Promotion of breast cancer metastasis by tumour hypoxia and myeloid cells.
  • 批准号:
    246608
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2011
  • 负责人:
    Bennewith Kevin L
  • 依托单位:
海外基金