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Role of astroglia in the behavioural and cellular effects of chronic stress and depression

Role of astroglia in the behavioural and cellular effects of chronic stress and depression
星形胶质细胞在慢性压力和抑郁的行为和细胞效应中的作用
批准号：
454624
负责人：
Bansal Yashika
金额：
$9.83万
依托单位：
Centre for Addiction and Mental Health (Toronto)
依托单位国家：
加拿大
项目类别：
Fellowship Programs
财政年份：
2021
资助国家：
加拿大
项目状态：
已结题
起止时间：
2021-10-01 至 2024-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=454624&lang=en
关键词：
Astroglial Dysfunction Behavioural Rodent Paradigms Calcium Fiber Photometry Chronic Stress Glutamate Transporter-1 Major Depressive Disorder Prefrontal Cortex Single Cell Rna Sequencing Synaptic Deficits Unpredictable Chronic Mild Stress

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Depression is a debilitating mental illness, affecting over 264 million people worldwide and ~3.2 million people in Canada. The modest efficacy of current antidepressant therapies compels a better understanding of the mechanisms involved in the developmen
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