Exploiting lipid-laden macrophages to overcome resistance to cancer immunotherapy
利用富含脂质的巨噬细胞克服癌症免疫疗法的耐药性
基本信息
- 批准号:460419
- 负责人:
- 金额:$ 19.69万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Operating Grants
- 财政年份:2021
- 资助国家:加拿大
- 起止时间:2021-12-01 至 2024-12-01
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Cancer immunotherapy has revolutionized cancer care, but its efficacy is dependent on the presence and activity of T cells within the tumor. We have discovered a unique immune cell type that consumes fat (lipids) from its surroundings, called "lipid-laden
癌症免疫疗法彻底改变了癌症治疗,但其疗效取决于肿瘤内T细胞的存在和活性。我们已经发现了一种独特的免疫细胞类型,它消耗周围的脂肪(脂质),称为“脂质负载”
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Quail Daniela其他文献
Quail Daniela的其他文献
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{{ truncateString('Quail Daniela', 18)}}的其他基金
Targeting obesity-associated monocytosis in colorectal cancer liver metastasis
针对结直肠癌肝转移中与肥胖相关的单核细胞增多
- 批准号:
444799 - 财政年份:2021
- 资助金额:
$ 19.69万 - 项目类别:
Operating Grants
Impact of obesity-associated inflammation on breast cancer progression
肥胖相关炎症对乳腺癌进展的影响
- 批准号:
379537 - 财政年份:2018
- 资助金额:
$ 19.69万 - 项目类别:
Operating Grants
Canada Research Chair - Tier 2 - CIHR Funded
加拿大研究主席 - 第 2 级 - CIHR 资助
- 批准号:
384933 - 财政年份:2017
- 资助金额:
$ 19.69万 - 项目类别:
Tumour-stroma interactions during breast-to-brain metastasis
乳腺脑转移过程中肿瘤与基质的相互作用
- 批准号:
269570 - 财政年份:2012
- 资助金额:
$ 19.69万 - 项目类别:
Fellowship Programs
Nodal promotes breast cancer metastasis and plasticity.
节点促进乳腺癌转移和可塑性。
- 批准号:
206192 - 财政年份:2009
- 资助金额:
$ 19.69万 - 项目类别:
Studentship Programs
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