Evaluating the synergistic effect of MG1 infection and SMAC mimetic treatment on latently HIV-infected cells

评估 MG1 感染和 SMAC 模拟治疗对潜伏 HIV 感染细胞的协同作用

• 批准号: 466687
• 负责人: Ameeriar Yasmeen
• 金额: $ 1.27万
• 依托单位: University of Ottawa
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-12-01 至 2022-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=466687&lang=en
• 关键词: Apoptosis; Cd4+ T-Cell; Hiv; Hiv Latency; Hiv Reservoir; Maraba Virus; Mg1; Oncolytic Virus; Smac Mimetics

Human immunodeficiency virus (HIV) primarily infects immune cells. This results in weakened immune function with the inability to fight infection, and if left untreated, HIV can develop into AIDS. There is no cure for HIV as this virus can incorporate its

人类免疫缺陷病毒（HIV）主要感染免疫细胞。这导致免疫功能减弱，无法抵抗感染，如果不及时治疗，HIV可能发展成艾滋病。目前还没有治愈艾滋病毒的方法，因为这种病毒可以合并其自身