Dark microglia's relationships with Alzheimer's disease hallmarks in late-onset patients.

暗小胶质细胞与阿尔茨海默病的关系是晚发患者的标志。

• 批准号: 460535
• 负责人: Lau Victor
• 金额: --
• 依托单位: University of Victoria (British Columbia)
• 依托单位国家: 加拿大
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-01-01 至 2023-01-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=460535&lang=en
• 关键词: Cellular Senescence; Collaboration With People With Lived Experience; Correlative Study; Electron Microscopy; Late-Onset Alzheimer'S; Microglia Subtypes; Prefrontal Cortex, Braak Stages Iii-Iv; Tau Pathology: Neuritic Plaques, Neurofibrillary Tangles

Late-onset Alzheimer's disease (LOAD), which occurs after the age of 65 and comprises most cases of Alzheimer's disease involves progressive memory loss and neuronal cell death in the brain. As current approaches towards comprehending Alzheimer's have not

迟发性阿尔茨海默病（LOAD），发生在65岁之后，包括大多数阿尔茨海默病病例，涉及进行性记忆丧失和大脑中的神经元细胞死亡。由于目前理解阿尔茨海默氏症的方法还没有