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Characterizing tissue-intrinsic barriers to malignant transformation in the breast epithelium

Characterizing tissue-intrinsic barriers to malignant transformation in the breast epithelium
描述乳腺上皮恶性转化的组织内在障碍
批准号:
468832
负责人:
McCaffrey Luke M
金额:
$76.35万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2022
资助国家:
加拿大
项目状态:
未结题
起止时间:
2022-09-01 至 2027-09-01

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中文摘要
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英文摘要
Epithelial cells are major components of most tissues in our body, and are the target of approximately 90% of all human cancers. Epithelial cells are able to self-assemble into organized structures such as ducts and alveoli. A hallmark of cancer progressi
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会议论文
Overcoming suppressive micro-environments in early breast cancer progression
  • 批准号:
    420525
  • 项目类别:
    Operating Grants
  • 资助金额:
    $97.53万
  • 财政年份:
    2020
  • 负责人:
    McCaffrey Luke M
  • 依托单位:
Targeting novel cancer-promoting pathways in breast cancer
  • 批准号:
    407424
  • 项目类别:
    Operating Grants
  • 资助金额:
    $4.37万
  • 财政年份:
    2019
  • 负责人:
    McCaffrey Luke M
  • 依托单位:
Distinct roles for the Par6 polarity protein in development of low- and high-grade breast cancers.
  • 批准号:
    368619
  • 项目类别:
    Operating Grants
  • 资助金额:
    $65.48万
  • 财政年份:
    2017
  • 负责人:
    McCaffrey Luke M
  • 依托单位:
Cell polarity in mammary morphogenesis and cancer
  • 批准号:
    237582
  • 项目类别:
    Operating Grants
  • 资助金额:
    $53.49万
  • 财政年份:
    2011
  • 负责人:
    McCaffrey Luke M
  • 依托单位:
海外基金