Conserved structural dynamics of outer-membrane channels in Acinetobacter baumannii as potential drug targets

鲍曼不动杆菌外膜通道的保守结构动力学作为潜在的药物靶点

• 批准号: 472344
• 负责人: Mercier Evan
• 金额: $ 7.29万
• 依托单位: Universit de Sherbrooke
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-09-01 至 2023-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=472344&lang=en
• 关键词: Efflux Pumps; Pre-Steady-State Kinetics; Single-Molecule Biophysics; Structural Dynamics

Antibiotics are used to treat bacterial infections and are a critical part of healthcare in Canada and worldwide. Unfortunately, bacteria are, more and more frequently, becoming resistant to the antibiotics we have, which weakens the effectiveness of anti

抗生素用于治疗细菌感染，是加拿大和全球医疗保健的重要组成部分。不幸的是，细菌越来越频繁地对我们拥有的抗生素产生耐药性，这削弱了抗病毒药物的有效性。