Defining the role of macrophages in fetal lung underdevelopment and the immunomodulatory effects of stem cell extracellular vesicle treatment

定义巨噬细胞在胎儿肺发育不良中的作用以及干细胞胞外囊泡治疗的免疫调节作用

• 批准号: 473703
• 负责人: Figueira Rebeca
• 金额: $ 9.83万
• 依托单位: Hospital for Sick Children (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-10-01 至 2025-10-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=473703&lang=en
• 关键词: Congenital Diaphragmatic Hernia; Exosomes; Extracellular Vesicle; Fetal Medicine; Fetal Therapy; Lung Develpoment; Lung Macrophage; Pulmonary Hypoplasia; Regenerative Medicine; Stem Cells

Every year in Canada, 180 babies are born with congenital diaphragmatic hernia (CDH), a birth defect caused by a hole in the muscle that separates the chest from the belly. As the organs in the belly move to the chest, the lungs have little room to grow r

在加拿大，每年有 180 名婴儿出生时患有先天性膈疝 (CDH)，这是一种由于分隔胸部和腹部的肌肉上出现洞而导致的出生缺陷。当腹部的器官移至胸部时，肺部几乎没有生长空间。