Developing necroptosis for breast cancer immunotherapy

开发用于乳腺癌免疫治疗的坏死性凋亡

• 批准号: 488239
• 负责人: Workenhe Samuel Tekeste
• 金额: $ 4.55万
• 依托单位: University of Guelph
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2023
• 资助国家: 加拿大
• 起止时间: 2023-02-01 至 2024-02-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=488239&lang=en
• 关键词: Immunotherapy; Oncolytic Viruses & Immunotherapy; Translational Research

Stressed and dying cellssend several messagesthat educate immune cells whether a danger is apparent or not. We identified that killing tumors with after activating a necroptotic death createsimmune stimulation to provide strong anticancer immunity. By pro

应激和垂死的细胞会发出几个信息，教育免疫细胞是否有明显的危险。我们发现，在激活坏死性死亡后杀死肿瘤是一种免疫刺激，可以提供强大的抗癌免疫力。利用pro