Accelerated Lung Aging in People Living with Human Immunodeficiency Virus

人类免疫缺陷病毒感染者的肺部老化加速

• 批准号: 483581
• 负责人: Leung Janice
• 金额: $ 7.29万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2023
• 资助国家: 加拿大
• 起止时间: 2023-03-01 至 2024-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=483581&lang=en
• 关键词: Aging; Copd; Epigenetics; Hiv; Imaging

People living with human immunodeficiency virus (PLWH, HIV) face a higher burden of aging-related chronic lung disease. There are signals of aging in the cells of the lung that we can capture and use to predict those PLWH who may go on to have more severe

人类免疫缺陷病毒（PLWH，HIV）感染者面临着与衰老相关的慢性肺部疾病的更高负担。在肺细胞中有老化的信号，我们可以捕捉并使用这些信号来预测那些可能继续患有更严重的PLWH的人。