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Waking up Hepatitis B virus (HBV)'s chronic form to maximize attack by promoter-targeting therapies

Waking up Hepatitis B virus (HBV)'s chronic form to maximize attack by promoter-targeting therapies
唤醒乙型肝炎病毒 (HBV) 的慢性形式,通过启动子靶向疗法最大限度地发挥攻击作用
批准号:
486942
负责人:
Kasinyabo Emmanuelle
金额:
$0.44万
依托单位:
依托单位国家:
加拿大
项目类别:
Miscellaneous Programs
财政年份:
2023
资助国家:
加拿大
项目状态:
已结题
起止时间:
2023-05-01 至 2023-09-01

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英文摘要
INTRO: Hepatitis B virus (HBV) remains chronic due to the persistence of its chronic form, the covalently closed circular DNA (cccDNA), which remains hidden in the nucleus, wrapped around histones and untargeted by current therapies. Thus, in the strategy
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